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RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression.
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of silencing gene expression in a range of organisms. The silencing of a gene is a consequence of degradation of RNA into short RNAs that activate ribonucleases to target homologous mRNA.
Nov 9, 2017 · RNA interference or Post-Transcriptional Gene Silencing is a conserved biological response to double-stranded RNA that mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
Jul 31, 2019 · RNA interference (RNAi) is the biological process of mRNA degradation induced by complementary sequences double-stranded (ds) small interfering RNAs (siRNA) and suppression of target gene expression.
RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes.
Sep 15, 2004 · At the heart of RNA interference lies a remarkable RNA processing mechanism that is now known to underlie many distinct biological phenomena.
Feb 26, 2024 · Two decades of research on RNA interference (RNAi) have transformed a breakthrough discovery in biology into a robust platform for a new class of medicines that modulate mRNA expression.
RNA interference (RNAi) is a natural process that occurs in cells where small RNA molecules ‘silence’ or decrease the activity of specific genes by preventing them from making proteins.
Apr 30, 2021 · RNA silencing is a highly conserved gene regulation mechanism in which small RNA molecules silence gene expression by either suppressing transcription (transcriptional gene silencing) or by triggering a sequence-specific degradation of target mRNA, a process known as posttranscriptional gene silencing or RNA interference (RNAi).
Jun 10, 2024 · RNA interference uses short RNA sequences complementary to a transcript of interest to decrease gene expression through transcriptional or translational silencing. Also known as: RNAi, knockdown (different from knock-out); shRNA (“hairpins”) or siRNA
