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Oct 15, 2015 · Solitary fibrous tumor (SFT) is a mesenchymal tumor of fibroblastic type that is poorly understood. Originally regarded as separate entities, SFT and hemangiopericytoma are now considered one neoplasm. In the 2013 WHO classification of soft tissue tumors, the terminology is unified under SFT only. These tumors exhibit fibroblastic-type ...
CD99 (or other immature T cell markers such as TdT and Cd1a) is particularly useful in evaluating mediastinal and other biopsy samples of possible thymic epithelial neoplasms and in the subtyping of these tumors ( Am J Surg Pathol 1997;21:936, Diagn Pathol 2007;2:13 )
A. All tumors show reactivity for CD34 B. Fat forming solitary fibrous tumors usually occur in younger adults, predominantly in females C. Multivacuolated lipoblasts are more common in the malignant subset D. The imaging findings of fat forming solitary fibrous tumor are specific E. The mediastinum is the most commonly affected site Stains:
Aug 30, 2021 · Although solitary fibrous tumors (SFTs) have an unpredictable evolution, some specific clinicopathologic factors have been associated with the final outcome. We retrieved clinical, pathological and molecular data of 97 patients with a histological diagnosis of SFT and Signal transducer and activator of transcription 6 (STAT6) positivity.
Nov 11, 2021 · Essential features. Soft tissue tumor of intermediate malignancy (locally aggressive), with no metastatic potential. Characterized by the presence of pleomorphic cells, low mitotic activity, ectatic blood vessels with damaged walls and no necrosis. Most cases are positive for CD34 and lack expression of S100, desmin, pankeratin and STAT6.
Mar 1, 2017 · Solitary fibrous tumors (SFTs) were first described in pleura in 1931. 1 Since then, nonpleural SFTs have been described as originating from almost every anatomic location of the human body, but reports of SFTs in the abdominal cavity are rare. 2 Five SFT cases arising from the stomach have been reported as of November 2016. 3 - 7.
Mar 4, 2011 · The pathological enigma surrounding solitary fibrous tumor is twofold. The first is identifying those tumors which have malignant potential and the second is the histological diagnosis of dedifferentiated solitary fibrous tumors. Most solitary fibrous tumors behave in a benign fashion. When arising from the pleura, 13-23% are classified as ...
