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      • Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass.
      www.mayoclinic.org/diseases-conditions/male-hypogonadism/diagnosis-treatment/drc-20354886
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  2. Mar 17, 2018 · Combined primary and secondary hypogonadism results in low T concentrations, impairment of spermatogenesis, and variable gonadotropin levels, depending on whether primary or secondary hypogonadism predominates.

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      Primary Hypogonadism. Secondary Hypogonadism.; ORGANIC KS:...

  3. Mar 19, 2018 · Recommends making a diagnosis of hypogonadism only in men with symptoms and signs consistent with testosterone (T) deficiency and unequivocally and consistently low serum T concentrations.

  4. The Endocrine Society recommends diagnosing testicular hypogonadism only in men with signs and symptoms consistent with TD (Table 1 5) and unequivocally and consistently low serum testosterone...

  5. Restoration of testosterone levels to the normal range improves libido, sexual function, and mood; reduces fat body mass; increases lean body mass; and improves bone mineral density.

    • P Dandona, M T Rosenberg
    • 10.1111/j.1742-1241.2010.02355.x
    • 2010
    • Int J Clin Pract. 2010 May; 64(6): 682-696.
  6. Oct 5, 2017 · An understanding of longitudinal studies of men with late onset hypogonadism following TRT across primary and secondary care has the potential to yield significant morbidity and mortality benefits for our patients.

    • Mark Livingston, Anura Kalansooriya, Andrew J. Hartland, Sudarshan Ramachandran, Adrian Heald, Adria...
    • 10.1111/ijcp.12995
    • 2017
    • Int J Clin Pract. 2017 Nov; 71(11): e12995.
  7. Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism. Clin Endocrinol (Oxf). 2022 Feb;96 (2):200-219. doi: 10.1111/cen.14633. Epub 2021 Nov 22. Authors.

  8. For men who have the diagnosis of primary or secondary hypogonadism with symptoms referable to consistently low serum testosterone levels, testosterone replacement should be offered because most studies show that benefits outweigh potential risks.