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There are two commonly used classifications for PNI- the Seddon Classification and the Sunderland Classification. Seddon is responsible for classifying peripheral nerve injuries into neuropraxia, axonotmesis, and neurotmesis.
Nerve injury classification assists in prognosis and determination of treatment strategy for nerve injuries. Classification was described by Seddon in 1943 and by Sunderland in 1951. In the lowest degree of nerve the nerve remains intact, but signaling ability is damaged, termed neurapraxia.
In 1953, Sunderland expanded Seddon’s classification from three to five degrees of peripheral nerve injury. The injuries are arranged in ascending order of severity from the first to the fifth degree and affect successively (1) conduction in the axon, (2) the continuity of the axon.
Jun 15, 2024 · Peripheral nerve injuries encompass a range of reversible and irreversible impairments determined by injury level, axonal disruption, and time to treatment. Diagnosis can be made based on clinical examination and confirmed with EMG/NCS.
Aug 7, 2023 · On the other hand, the Sunderland classification has five grades based on the severity of the injury. The first corresponds to neuropraxia in Seddon’s classification and includes nerve conduction block due to focal myelin sheath disruption.
The two widely used major classifications for nerve injury grading are the Seddon and Sunderland classifications.[4,5,6,7] While Seddon classification is simpler to follow and more relevant to electrophysiologists, Sunderland grading is more often used by surgeons to decide when and how to intervene.
Sunderland later expanded on this classification to distinguish the extent of damage in the connective tissues 7. In his classification scheme, Grade I and Grade V corresponded with Seddon's neurapraxia and neurotmesis respectively.
