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  1. Aug 7, 2023 · Pathophysiology. COPD is an inflammatory condition involving the airways, lung parenchyma, and pulmonary vasculature. The process is thought to involve oxidative stress and protease-antiprotease imbalances.

  2. Sep 26, 2021 · Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily caused by cigarette smoke (CS).

  3. Dec 28, 2022 · Chronic obstructive pulmonary disease (COPD) is quite common – even more common than asthma. One of the typical symptoms is a persistent cough. In advanced COPD, it is difficult to breathe.

  4. Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational exposures are less common causes in patients who do not smoke.

  5. Nov 12, 2018 · Chronic obstructive pulmonary disease (COPD) is a life-threatening condition that affects your lungs and your ability to breathe. Pathophysiology is the evolution of adverse functional...

  6. May 18, 2006 · Chronic obstructive pulmonary disease (COPD) is characterised by poorly reversible airflow obstruction and an abnormal inflammatory response in the lungs. The latter represents the innate and adaptive immune responses to long term exposure to noxious particles and gases, particularly cigarette smoke.

  7. Key facts. Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, causing 3.23 million deaths in 2019. Nearly 90% of COPD deaths in those under 70 years of age occur in low- and middle-income countries (LMIC). COPD is the seventh leading cause of poor health worldwide (measured by disability-adjusted life years)

  8. Apr 15, 2020 · Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing.

  9. Sep 25, 2019 · Pathological Features of Smoking-Induced COPD. The severity of airflow limitation in COPD is associated with the extent to which the lung tissue is infiltrated by neutrophils, macrophages, and...

  10. Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational exposures are less common causes in nonsmokers.

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