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Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Stimulates research on the basis of mechanisms of apoptosis and its role in various human disease processes.
Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized : apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. [1] Biochemical events lead to characteristic cell changes ( morphology) and death. [2]
The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms.
Programmed Cell Death (Apoptosis) The cells of a multicellular organism are members of a highly organized community. The number of cells in this community is tightly regulated—not simply by controlling the rate of cell division, but also by controlling the rate of cell death.
Jun 6, 2017 · Apoptosis is a process that occurs in multicellular when a cell intentionally “decides” to die. This often occurs for the greater good of the whole organism, such as when the cell's DNA has become damaged and it may become cancerous.
Apr 30, 2024 · Many years later, apoptosis is defined as the ATP-dependent, enzyme-mediated, genetically programmed death of cells that are either no longer required or pose a threat to the organism. Apoptosis results when the cytoskeleton (by proteases) and DNA (by endonucleases) break down through several pathways that are homeostatic or pathological.
May 23, 2024 · apoptosis, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then disposed of in an orderly fashion.
Apoptosis is a form of programmed cell death, or “cellular suicide.” It is different from necrosis, in which cells die due to injury. Apoptosis is an orderly process in which the cell’s contents are packaged into small packets of membrane for “garbage collection” by immune cells.
Jan 17, 2019 · Apoptosis is an evolutionarily conserved cell death pathway that is responsible for the programmed culling of cells during normal eukaryotic development and maintenance of organismal homeostasis.
Mar 30, 2021 · Here, we summarize the latest discoveries in the three most well understood modalities of cell death, namely, apoptosis, necroptosis, and pyroptosis, highlighting common and unique pathways and...
