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The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.
SCOPe (Structural Classification of Proteins — extended) is a database developed at the Berkeley Lab and UC Berkeley to extend the development and maintenance of SCOP. SCOP was conceived at the MRC Laboratory of Molecular Biology, and developed in collaboration with researchers in Berkeley.
The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins.
Jan 1, 2001 · The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of known protein structures.
Jun 25, 2024 · The SCOP database classifies non-redundant protein domains. Representative proteins are selected based on sequence (UniProtKB) and structure (PDB) for manual SCOP classification. The classification of the representative is then automatically extended to related entries using SIFTS.
Jun 25, 2024 · The SCOP and SCOPe database provides a broad survey of all known protein folds, detailed information about close relatives of the protein of interest, and a framework for research and classification. Using the SCOP browser you can identify proteins that have domains that are related by structure and may share evolutionary origins.
Jan 1, 2014 · In this article, we describe SCOP—extended (SCOPe), a database that extends SCOP 1.75, with the aim of providing ongoing classification of new PDB structures in the context of the SCOP hierarchy, backward compatibility with SCOP, manual correction of errors and stable releases suitable for benchmarking.
The Structural Classification of Proteins — extended ( SCOPe) knowledgebase aims to provide an accurate, detailed, and comprehensive description of the structural and evolutionary relationships amongst all proteins of known structure, along with resources for analyzing the protein structures and their sequences.
Structural Classification of Proteins — extended (SCOPe) is a database of protein structural relationships that extends the SCOP database. SCOP is a (mostly) manually curated ordering of domains from the majority of proteins of known structure in a hierarchy according to structural and evolutionary relationships.
The SCOP-e database aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.
