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Current Drug Targets aims to cover developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. receptors, enzymes, genes.
1 day ago · Read the latest articles of Current Cancer Drug Targets at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature.
Feb 20, 2024 · According to the official website of China’s National Medicines and Pharmaceutical Administration (NMPA), a total of 87 novel drugs were approved in China in 2023, with targeted drugs accounting...
May 3, 2023 · Here, we focus on the 12 drugs approved in 2022 with novel MoA targets (Table 1). These targets have not been modulated by any previously approved drug.
Dec 2, 2016 · Here, Overington and colleagues present a comprehensive map of the molecular targets of approved drugs, and explore aspects including the footprint of target classes across disease areas, the...
Jul 17, 2021 · After initial strategies targeting inotropism and congestion, the neurohormonal interpretative model of heart failure (HF) pathophysiology has set the basis for current pharmacological management of HF, as most of guideline recommended drug classes, including beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers,...
Dec 23, 2021 · A recent development of new therapeutic agents and novel drug targets for cancer treatment - PMC. Journal List. SAGE Open Med. v.9; 2021. PMC8725032. As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health.
6 days ago · Drug trafficking is empowering organized crime groups. Drug traffickers in the Golden Triangle are diversifying into other illegal economies, notably wildlife trafficking, financial fraud, and illegal resource extraction. Displaced, poor, and migrant communities are suffering the consequences of this instability, sometimes forced to turn to opium farming or illegal resource extraction to survive, falling into debt entrapment with crime groups, or using drugs themselves. ...
Apr 15, 2024 · Studies in polypharmacology could reveal new off-targets for current drugs, offering insight into drug side effects and toxicities.
May 13, 2024 · The emergence of small nucleic acid drugs as a focal point in contemporary biopharmaceutical research is attributed to their remarkable specificity, facile design, abbreviated development cycles, expansive target spectrum, and prolonged activity.
