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  1. Aug 23, 2022 · Niacin deficiency, known as pellagra, is serious and life-threatening. Symptoms may be mild initially but can escalate to severe digestive, skin, and nervous system problems. Many foods are fortified with niacin. You can also get niacin by taking dietary supplements.

  2. Jul 25, 2023 · Niacin (vitamin B3) deficiency results in a condition known as pellagra. Pellagra includes the triad of dermatitis, dementia, and diarrhea and can result in death. In addition, niacin deficiency can occur through genetic disorders, malabsorptive conditions, and interaction with certain medications.

  3. Jun 6, 2023 · Niacin deficiency is a condition that occurs when a person doesn't get enough or can't absorb niacin or its amino acid precursor, tryptophan. In the United States, niacin deficiency is...

  4. Diagnosis of niacin deficiency is clinical and may be straightforward when skin and mouth lesions, diarrhea, delirium, and dementia occur simultaneously. More often, the presentation is not so specific. Differentiating the central nervous system changes from those in thiamin deficiency is difficult.

  5. Niacin deficiency (causing pellagra) is uncommon in countries with low rates of food insecurity. Many people with niacin deficiency also have deficiencies of protein, riboflavin (a B vitamin), and vitamin B6. A distinctive dark red rash appears on the hands, feet, calves, neck, and face, and the tongue and mouth turn dark red.

  6. Symptoms and Signs. Diagnosis. Treatment. Key Points. Dietary niacin deficiency (causing pellagra) is uncommon in countries with low rates of food insecurity. Clinical manifestations include the three Ds: localized pigmented rash (dermatitis); gastroenteritis (diarrhea); and widespread neurologic deficits, including cognitive decline (dementia).

  7. Causes. Symptoms. Diagnosis. Treatment. Niacin deficiency (causing pellagra) is uncommon in countries with low rates of food insecurity. Many people with niacin deficiency also have deficiencies of protein , riboflavin (a B vitamin), and vitamin B6 .

  8. Dec 21, 2023 · Vitamin B3 deficiency is traditionally caused by consuming a diet mainly composed of corn and maize. Severe deficiency leads to pellagra, which is characterised by dermatitis, dementia, diarrhoea, and eventually death. Lean meat, poultry, fish, and peanuts are rich in vitamin B3 (niacin); milk an...

  9. A severe niacin deficiency has been associated with cognitive decline such as memory loss and dementia. Niacin is believed to protect brain cells from stress and injury. It is not yet clear though if smaller variations in dietary niacin intake can negatively affect brain function.

  10. Feb 21, 2019 · Niacin, or vitamin B-3, is essential for preventing pellagra, the symptoms of which include skin problems, diarrhea, and dementia. It may have some use in medicine, but consuming too much can...