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This server provides access to the program Genscan for predicting the locations and exon-intron structures of genes in genomic sequences from a variety of organisms. This server can accept sequences up to 1 million base pairs (1 Mbp) in length.
In bioinformatics, GENSCAN is a program to identify complete gene structures in genomic DNA. It is a G HMM -based program that can be used to predict the location of genes and their exon - intron boundaries in genomic sequences from a variety of organisms. The GENSCAN Web server can be found at MIT. [1]
A repository of bioinformatics software and databases developed in the Chris Burge lab at MIT. All software produced by our lab is available (by download or by request from the author) free of charge by academic and other non-profit researchers.
GENSCAN was developed by Chris Burge in the research group of Samuel Karlin, Department of Mathematics, Stanford University. The program and the model that underlies it are described in: Burge, C. and Karlin, S. (1997) Prediction of complete gene structures in human genomic DNA.
Aug 12, 2007 · GENSCAN was easy to use, very fast, and predicted genes in the long sequences of genomic DNA that would characterize the human genome project. Although subsequently shown to predict only 10-15% of genes correctly on realistic genome-wide datasets [4,5], GENSCAN remains a popular bioinformatics tool.
GenScan can accept and analyze nucleotide sequences of up to one million base pairs in length. It can analyze the sequence of either one or both the stands of a DNA duplex and make consistent prediction of groups of genes. GenScan has high accuracy but is sensitive to exon length.
Oct 12, 1999 · One of the first useful products from the human genome will be a set of predicted genes. Besides its intrinsic scientific interest, the accuracy and completeness of this data set is of considerable importance for human health and medicine.
Jun 22, 2018 · EVIDENCE_BASIS provides reference to a database entry (including accession and version) or an algorithm (including version). The accession.version number of a database record and the version number of an algorithm are separated from the database or algorithm name by a colon, as seen in the examples.
Jul 1, 2001 · Gene finding is a chief aspect of nucleotide-level annotation. For complex genomes, the most successful methods use a combination of ab initio gene prediction and sequence comparison with...
GENSCAN correctly predicts an ORF at ∼ 10% of human gene loci that contain a known ORF (gene sensitivity). The next major improvement came in 2001, with the advent of dual-genome de novo...
