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  1. Mar 20, 2024 · This activity introduces the epidemiology, pathophysiology, diagnostic approaches, and treatments of latent and active TB.

  2. Tuberculosis causes a primary, often asymptomatic infection followed by latent infection and, in a few patients, an active disease phase. About one fourth of the world's population is infected with tuberculosis, and about 15 million have active disease at a given time.

  3. Mar 20, 2013 · Using rabbit models, Dr. Arthur Dannenberg described the pathology of tuberculosis in detail [ 2, 3 ]. There are five stages: onset, symbiosis, early stages of caseous necrosis, interplay of cell-mediated immunity and tissue damaging delayed-type hypersensitivity, and liquefaction and cavity formation.

  4. Chapter 2 Pathogenesis. In this section the different phases of infection with Mycobacterium tuberculosis will be reviewed. Starting from transmission by inhalation, to the innate and adaptive immune response and the dual role of tuberculoma formation in walling off infection, but also providing an advantageous environment for bacilli to ...

  5. Oct 27, 2016 · Tuberculosis (TB) is an airborne infectious disease caused by organisms of the Mycobacterium tuberculosis complex. Although primarily a pulmonary pathogen, M. tuberculosis can cause disease in...

  6. Mar 5, 2024 · M. tuberculosis causes tuberculosis (TB) and is a leading infectious cause of death in adults worldwide [ 1 ]. (See "Epidemiology of tuberculosis" .) The microbiology, pathogenesis, and immunology of TB will be reviewed here.

  7. Mar 22, 2023 · Tuberculosis is caused by a bacterium called Mycobacterium tuberculosis. People with active TB disease in the lungs or voice box can spread the disease. They release tiny droplets that carry the bacteria through the air.

  8. Summary. Tuberculosis remains the leading cause of death from an infectious disease among adults worldwide, with more than 10 million people becoming newly sick from tuberculosis each year.

  9. Jan 2, 2023 · The major pathology in tuberculosis is necrotizing granulomatous inflammation, with the lungs being the primary organs of involvement of the disease in up to 87% of the cases. Having that said, almost any bodily organ could be a site for the disease.

  10. Jul 2, 2022 · Tuberculosis (TB) is an infectious disease of epidemic proportions, fired not only by poverty and human immunodeficiency virus (HIV) infection but also by incomplete understanding of its pathogenesis and lack of access to accurate and rapid diagnosis.