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  1. Aug 14, 2023 · The causes of fever of unknown origin (FUO) are often common conditions presenting atypically. The list of causes is extensive, and it is broken down into broader categories, such as infection, noninfectious inflammatory conditions, malignancies, and miscellaneous.

  2. Oct 15, 2010 · Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits. Common causes are infections, neoplasms, and connective tissue disorders.

  3. Pyrexia of unknown origin (PUO), also known as fever of unknown origin (FUO), is a grouping of many unrelated medical conditions that share the feature of persistent unexplained fever despite basic investigation.

  4. Fever of unknown origin ( FUO) refers to a condition in which the patient has an elevated temperature ( fever) but, despite investigations by one or more qualified physicians, no explanation is found. [1] [2] [3] If the cause is found it is usually a diagnosis of exclusion, eliminating all possibilities until only the correct explanation remains.

  5. The syndrome of pyrexia of unknown origin (PUO) was first defined in 1961 but remains a clinical challenge for many physicians. Different subgroups with PUO have been suggested, each requiring different investigative strategies: classical, nosocomial, neutropenic and HIV-related.

  6. Nov 28, 2023 · Clinicians commonly refer to a febrile illness without an initially obvious etiology as fever of unknown origin (FUO). However, most febrile illnesses either resolve before a diagnosis can be made or develop distinguishing characteristics that lead to a diagnosis.

  7. Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient investigations....

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