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ICEGATE (Indian Customs EDI Gateway) is an e-commerce portal of the Indian Customs which offers services such as e-filing of Bills of Entry (Import Goods Declaration);Shipping Bills (Export Goods Declaration); and EDI between Customs and its Trade Partners for IGM, EGM, Customs Duty Payment and Drawback Disbursal through electronic messages.
Dec 19, 2022 · IgM is the first antibody secreted by the adaptive immune system in response to a foreign antigen. Monomeric IgM is a heterotetramer of approximately 180 kDa. However, the secreted form of IgM exists predominantly in a pentameric configuration with a molecular weight greater than 900 kDa.
Immunoglobulin M ( IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen; [1] [2] causing it to also be called an acute phase antibody.
Dec 20, 2018 · IgM. IgM is the largest antibody and the first one to be synthesized in response to an antigen or microbe, accounting for 5% of all immunoglobulins present in the blood.
Dec 15, 2022 · Immunoglobulin M antibodies (IgM) are our first-line defense against a broad range of infections. They are often measured to help diagnose different conditions, such as infections, immunodeficiency, autoimmune disease, and certain types of cancer. Keep reading to learn more about high and low IgM levels and the factors that may affect them.
Jan 23, 2024 · Immunoglobulin M (IgM), the largest pentameric immunoglobulin is used as a marker of recent primary infection for some diseases and can be produced in T independent manner which also aids in disease diagnosis. IgM ELISA test can be performed to detect such antibodies in the serum of patients.
Jun 26, 2022 · IgM is the first immunoglobulin class to be synthesized by the neonate and plays a role in the pathogenesis of some autoimmune diseases. Although IgM antibodies usually have low-affinity binding sites for antigen, they have ten combining sites per molecule that can synergize with each other.
