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Paul Bunnell Test is used for detecting heterophil antibodies in infectious mononucleosis. This test uses sheep RBCs that are specially prepared. When these clump or aggregates, then they are put in blood samples of patients with heterophile antibodies.
Heterophil antibody tests such as the Paul Bunnell or Monospot tests may be used in the diagnosis of glandular fever. Heterophil antibodies have the ability to agglutinate red blood cells of different animal species. The Paul-Bunnell test uses sheep erythrocytes; the Monospot test, horse red cells. In infectious mononucleosis, IgM heterophil ...
It is an improvement on the Paul–Bunnell test. The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection. Commercially available test kits are 70–92% sensitive and 96–100% specific, with a lower sensitivity in the first two weeks after clinical symptoms begin.
The monospot test, also known as the Paul-Bunnell test, is a form of the heterophile antibody test used to rapidly screen infectious mononucleosis (mono). Epstein–Barr virus (EBV) causes the disease infectious mononucleosis.
Paul Bunnell. Actor: The Ghastly Love of Johnny X. It is said that Paul Bunnell was born in a popular movie theater in Burbank, California between showings of It's a Mad Mad Mad Mad World (1963) and The Nutty Professor (1963).
Jun 18, 2024 · Paul Bunnell test is used to find heterophil antibodies in cases of infectious mononucleosis. Specially prepared sheep red blood cells are used for this test. These are added to patient blood samples with heterophile antibodies when clumping or aggregating.
The heterophile antibody response to Epstein-Barr Virus (EBV) that gives a positive result is usually detectable between the 5th and 10th day of illness, reaching a peak in the second to third week and persisting for several months.
