Yahoo India Web Search

Sign In

Search results

  1. www.ncbi.nlm.nih.gov › pmc › articlesA Novel Combretastatin A‐4 Derivative, AC‐7700, Shows Marked ...

    Yukio Nihei, 1 Yasuyo Suga, 1 Yoshihiro Morinaga, 1 Kazuo Ohishi, 1 Akira Okano, 1 Koji Ohsumi, 1 Toshihiro Hatanaka, 1 Ryusuke Nakagawa, 1 Takashi Tsuji, 1 Yukio Akiyama, 1 Sachiko Saito, 2 Katsuyoshi Hori, 2 Yasufumi Sato, 2 and Takashi Tsuruo 3

    • Yukio Nihei, Yasuyo Suga, Yoshihiro Morinaga, Kazuo Ohishi, Akira Okano, Koji Ohsumi, Toshihiro Hata...
    • 1999

  2. www.researchgate.net › Yukio-Nihei-2054451437Yukio Nihei's research works | AJINOMOTO CO., INC., Tokyo and ...

    Yukio Nihei's 12 research works with 933 citations and 386 reads, including: ChemInform Abstract: Novel Combretastatin Analogues Effective Against Murine Solid Tumors: Design and...

  3. www.ncbi.nlm.nih.gov › pmc › articlesCombination effect of AC‐7700, a novel combretastatin A‐4 ...

    The in vivo combination effect of AC‐7700, a novel combretastatin A‐4 derivative, and cisplatin (CDDP) was examined. The combination of AC‐7700 and CDDP increased antitumor activity against murine colon 26 tumor in mice and cured the mice.

  4. www.sciencedirect.com › science › articleNovel B-ring modified combretastatin analogues: Syntheses and ...

    Dec 1, 1998 · INTRODUCTION: Combretastatin A-4 (CA-4) (2) is one of the most potent antimitotic agents derived from Combretum caffrum and binds to tubulin at the colchicine binding site.1 This agent shows strong cytotoxicity against variety of human cancer cells including multi-drug resistant cancer cell lines.2 However, the low water-solubility of CA-4 limit...

    • Toshihiro Hatanaka, Koichi Fujita, Koji Ohsumi, Ryusuke Nakagawa, Yumiko Fukuda, Yukio Nihei, Yasuyo...
    • 1998

  5. pubmed.ncbi.nlm.nih.gov › 9685242Novel combretastatin analogues effective against murine solid ...

    Jul 30, 1998 · Abstract. A series of combretastatin A-4 (CA-4) analogues were synthesized, and their cytotoxic effects against murine Colon 26 adenocarcinoma and inhibitory activity on tubulin polymerization were evaluated.

  6. www.sciencedirect.com › science › articleSyntheses and antitumor activity of cis-restricted ...

    Nov 17, 1998 · A series of cis-restricted combretastatin analogues with 5-membered heterocycles were synthesized and their inhibitory activity against microtubule assembly and cytotoxic activity against the colon 26 adenocarcinoma cancer cell line were evaluated. Some of the heterocyclic analogues showed potent antitubulin activity and cytotoxicity.

  7. www.animenewsnetwork.com › encyclopedia › peopleYukio NIHEI - Anime News Network

    Mar 7, 2024 · Vinland Saga Season 2 voted by the public as Anime of the Year ― The jury, as well as the public has spoken, and announced their winners for the 2023 edition of the /r/anime community's annual ...