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  1. Graham Erwin, Ph.D., is an Assistant Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine. He is a molecular, chemical, and genome biologist elucidating the functional role of tandem repeat (TR) DNA sequences.

    • Research

      Graham S. Erwin, PhD - Research. Chemical Biology. Graham is...

    • Publications

      Erwin GS, Grieshop MP, Bhimsaria D, Eguchi A,...

  2. Articles 1–19. ‪Assistant Professor, Baylor College of Medicine‬ - ‪‪Cited by 326‬‬ - ‪Tandem Repeats‬ - ‪Chemical Biology‬ - ‪Gene Regulation‬.

  3. Graham likes studying repetitive DNA, synthesizing molecules to target repetitive DNA, and bringing people together to talk about repetitive DNA. He organizes the Structural Variants and DNA Repeats (SVAR) Conference every year.

  4. Dec 14, 2022 · In seven cancer types, we found 160 recurrent repeat expansions (rREs), most of which (155/160) were subtype specific. We found that rREs were non-uniformly distributed in the genome with ...

  5. Graham S. Erwin, PhD - Research. Chemical Biology. Graham is a co-inventor of synthetic transcription elongation factors (Syn-TEFs), a new class of TR-targeting compounds that reverse pathogenic gene expression.

  6. Expansion of a single repetitive DNA sequence, termed a tandem repeat (TR), causes more than 30 rare but devastating diseases. Despite their importance to monogenic disease, the frequency and function of repeat expansions are unknown in complex human diseases.

  7. Erwin GS, Grieshop MP, Bhimsaria D, Eguchi A, Rodríguez-Martínez JA, Ansari AZ. Genome-wide mapping of drug-DNA interactions in cells with COSMIC (crosslinking of small molecules to isolate chromatin) .