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Lieberman studies how certain viruses establish a long-term latent infection that can lead to cancer or autoimmune disorders. Lieberman joined The Wistar Institute in 1995 as an assistant professor.
Paul M. Lieberman is an American biomedical researcher and chairperson of the Gene Expression and Regulation Program at the Ellen and Ronald Caplan Cancer Center at The Wistar Institute in Philadelphia.
The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and …. PM Lieberman, JM...
Paul Lieberman, Ph.D., has developed a small molecule inhibitor of the EBV protein EBNA1 for EBV-associated malignancies. Preclinical development of this compound was largely supported by Wellcome, a biomedical research charity based in the United Kingdom.
Oct 28, 2021 · Description of Research Expertise. Research Interests. Genome maintenance and gene expression; Gammaherpesviruses and oncogenesis; Telomere Biology, Chromatin structure and genome stability; Transcription regulation. Key words: viral latency, telomeres, chromatin, DNA replication, transcription regulation, herpesvirus. Description of Research.
Oct 28, 2021 · Description of Research Expertise. Research Interests. Genome maintenance and gene expression; Gammaherpesviruses and oncogenesis; Telomere Biology, Chromatin structure and genome stability; Transcription regulation. Key words: viral latency, telomeres, chromatin, DNA replication, transcription regulation, herpesvirus. Description of Research.
Paul M. Lieberman, Ph.D. Contribution to Science. 1. Basic Mechanism of Transcription Regulation. My early scientific work focused on basic mechanisms of gene activation.
