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Aug 30, 2020 · Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin.
Oct 13, 2020 · T2DM, also known as non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes, as per the previous nomenclature, constitutes about 90–95% of all the cases of diabetes. This type of diabetes is characterized by two main insulin-related anomalies: insulin resistance and β-cell dysfunction.[27,28,29] Insulin resistance results ...
Jun 23, 2023 · Objectives: Describe the etiologies of diabetes mellitus. Review the pathophysiology of diabetes mellitus. Summarize the treatment options for diabetes mellitus. Review the importance of improving care coordination among interprofessional team members to improve outcomes for patients affected by diabetes mellitus type 2.
Mar 14, 2023 · The liver stores and makes glucose. When glucose levels are low, the liver breaks down stored glycogen into glucose to keep the body's glucose level within a healthy range. In type 2 diabetes, this process doesn't work well. Instead of moving into the cells, sugar builds up in the blood.
May 4, 2022 · Type 2 diabetes mellitus (T2DM) is a complex, heritable and heterogeneous condition that manifests in a range of phenotypes 1. Characterizing these phenotypes could reveal insights into the...
Jul 23, 2015 · Ram Weiss. Nature Reviews Disease Primers 1, Article number: 15019 ( 2015 ) Cite this article. 48k Accesses. 1067 Citations. 124 Altmetric. Metrics. Abstract. Type 2 diabetes mellitus (T2DM)...
Dec 5, 2019 · The integrative biology of type 2 diabetes. Michael Roden & Gerald I. Shulman. Nature 576 , 51–60 ( 2019) Cite this article. 76k Accesses. 605 Citations. 169 Altmetric. Metrics. Abstract....
