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  1. Jun 14, 2024 · Gleason score is a scale used to evaluate the aggressiveness of prostate cancer cells based on how they differ from healthy cells. Learn how Gleason score is determined and what it means for your prostate cancer treatment options.

  2. 6 days ago · Secondly, random sampling reveals clinically insignificant cancers (ciPCa), most frequently defined by the ‘Epstein’ criteria (Gleason Score 6 [3 + 3], less than 3 cores with cancer involvement, no core with cancer involvement ≥ 50% and a prostate-specific-antigen-density of < 0.15 ng/ml 2), which are unlikely to cause any symptoms in the patient’s lifetime, but might contribute to subsequent overtreatment once being diagnosed .

  3. Jun 27, 2024 · Gleason scores ranged from 5 to 10; two tumors had a Gleason score of 5; 22 tumors had a Gleason score of 6 or 7; and eight tumors had a Gleason score higher than 8. Sixty-seven percent (12 of 18) of the tumors were found to have perineural invasion, and 47% (9 of 19) had extracapsular invasion.

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  5. Jun 18, 2024 · Gleason score and grade groups are used to grade the metastatic potential of prostate adenocarcinoma based on gland-forming differentiation. Evaluation of tumor extent [21] [22] [33] mpMRI provides information on local tumor extent (e.g., tumor size and volume).

  6. 5 days ago · Approximately 8% of patients with a prostate biopsy result of Gleason grade group (GGG) 1 have occult high-risk prostate cancer. Maintaining the “cancer” classification for GGG 1 for cases with >50% positive systematic biopsy cores or prostate-specific antigen >20 ng/ml may minimize the risk of mortality for these patients.

  7. Jun 28, 2024 · The Gleason score is a tissue-based prognostic marker for prostate cancer that suffers from variability, leading to inconsistencies and classification errors.

  8. Jun 30, 2024 · Preoperative Gleason scores increased significantly across risk categories, from an average of 6.21 in low-risk patients to 7.57 in high-risk patients.

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