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  1. Aug 22, 2024 · Sunburn is an acute inflammatory skin condition characterised by erythema, oedema, vesiculation, and desquamation, with associated symptoms of pain and/or pruritus. Sunburn is a major preventable risk factor for accelerated photo-ageing and most common forms of skin cancer. It typically runs a self-limited course and is treated symptomatically.

  2. Jun 7, 2023 · Consider xeroderma pigmentosum (XP) in a young child (typically <2 years old) with early-onset severe and exaggerated sunburn with minimal sun exposure or with early and extensive freckle-like lesions (lentigines) in sun-exposed areas. Patients aged <20 years have a more than 1000-fold increased risk of cutaneous malignancies.

  3. Oct 14, 2022 · Sunburn is an acute inflammatory reaction of the skin induced by overexposure to UV radiation. Skin findings include erythema and oedema, with or without vesiculation, followed by desquamation. Symptoms include pain and/or pruritus. Acute sunburn is a self-limiting condition and typically requires only supportive care.

  4. Aug 30, 2011 · The ANC is calculated as follows: ANC = white blood cells (microlitre) x percent (polymorphonuclear cells + bands)/100. [ Absolute neutrophil count ] An ANC <1500/microlitre or <1.5 x 10⁹/L is defined as neutropenia and graded as follows: [3] As the ANC falls below 1000/microlitre or 1 x 10⁹/L, the risk of infection progressively increases.

  5. Oct 3, 2023 · Lipomas are slow-growing, benign, mesenchymal tumours that form well-circumscribed, lobulated lesions composed of adipocytes. They are demarcated from surrounding fat by a thin, fibrous capsule. They comprise 50% of soft-tissue neoplasms and are commonly encountered by primary care physicians, surgeons, and pathologists. [1] . Lipomas usually ...

  6. Mar 4, 2020 · Pityriasis versicolor is a superficial fungal infection of the stratum corneum, due to dimorphic yeasts of the genus Malassezia, leading to hypo- or hyperpigmented macular lesions on seborrheic areas of the trunk. Eruption is most common in the summer months in adolescents. Often has a relapsing nature requiring frequent treatment or prophylaxis.

  7. Feb 8, 2022 · Vitiligo is a common, acquired multifactorial skin disease. It is characterised by progressive depigmentation of the epidermis in circumscribed areas, typically without erythema or scaling. Age of onset is bimodal and involves a major genetic component. Multiple auto-immune disorders may be associated with vitiligo, most commonly auto-immune ...

  8. Apr 22, 2024 · Accidental hypothermia is characterised by the unintentional lowering of core body temperature below physiological normal limits, typically <35°C (<95°F). A threshold of 36°C (96.8°F) has been adopted in patients with trauma. In this patient group, even milder degrees of hypothermia have devastating consequences in both military and ...

  9. Jun 25, 2024 · Primary biliary cholangitis (PBC) is characterised by progressive intrahepatic bile duct damage and loss. PBC is significantly more common in women than in men. Peak incidence is around age 40 years, and median age at diagnosis is 65 years. The combination of a cholestatic pattern of serum liver tests (elevated alkaline phosphatase, gamma ...

  10. May 10, 2024 · Legionella infection is acquired by inhalation of aerosolised bacteria or, rarely, micro-aspiration of contaminated drinking water. Presentation includes respiratory symptoms such as cough (may not be productive) and shortness of breath, fever, chills, and chest pain. Other symptoms include headache, nausea, vomiting, abdominal pain, or diarrhoea.

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