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  1. Jul 12, 2024 · Usual interstitial pneumonia (UIP) is not a disease, it is a histopathologic and radiologic pattern of interstitial lung disease. This can be caused by idiopathic pulmonary fibrosis, fibrotic hypersensitivity pneumonitis or non-specific interstitial pneumonia. The diagnosis is typically decided by a multidisciplinary team. Terminology.

  2. Jun 19, 2024 · This helps radiologists to determine the certainty of usual interstitial pneumonia (UIP) diagnosis based on HRCT chest findings. The importance of this guideline is that (definite) UIP pattern on chest HRCT precludes the need for tissue diagnosis 1,2,5.

  3. Case Discussion. These findings are consistent with UIP pattern. UIP has distinctive HRCT findings. If the UIP pattern is of unknown cause (i.e. idiopathic), the disease is called idiopathic pulmonary fibrosis (IPF).

  4. Extensive pulmonary fibrosis characterized by peripheral inter and intralobular septal thickening, traction bronchiectasis, and micro and macrocytic honeycombing. These demonstrate a relative craniocaudal gradient of distribution.

  5. The presence of exuberant honeycombing and straight edge signs are highly suggestive of UIP secondary to the concomitant connective tissue disorder such as rheumatoid arthritis over the idiopathic pulmonary fibrosis (IPF). Further investigation showed that patient has positive rheumatoid factor and antinuclear antibody (ANA), managed by a ...

  6. This case shows typical UIP pattern on imaging: distribution. basal predominant. subpleural predominant. features. honeycombing. reticulation with peripheral bronchiectasis or bronchiolectasis. absence of features suggesting an alternative diagnosis.

  7. May 14, 2018 · Imaging Appearance: Usual interstitial pneumonia (UIP) is a radiologic and pathologic pattern of chronic fibrosing interstitial pneumonia. On high-resolution CT, it classically presents as basilar and sub-pleural predominant reticulation and traction bronchiectasis.

  8. Sep 3, 2016 · The interstitial pneumonias (IPs), or idiopathic interstitial pneumonias (IIPs), are a heterogeneous group of diffuse lung diseases characterized by varying degrees of lung inflammation and fibrosis. They are best thought of as reactions to lung injury, presenting with specific histologic patterns.

  9. Nov 15, 2017 · A usual interstitial pneumonia (UIP) pattern on chest CT scans is highly suggestive of UIP pathologic findings; the most common cause of UIP is idiopathic pulmonary fibrosis (IPF) [1–5]. Under current guidelines, a UIP pattern on CT images is specific for IPF after a thorough clinical and serologic workup has excluded other causes of ...

  10. May 23, 2024 · Non-specific interstitial pneumonia (NSIP) is the second most common morphological and pathological pattern of interstitial lung diseases after UIP. NSIP is commonly associated with connective tissue disease (CTD) and the underlying diagnosis and management are best decided by a multidisciplinary team.