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GENSCAN was developed by Chris Burge in the research group of Samuel Karlin, Department of Mathematics, Stanford University. The program and the model that underlies it are described in: Burge, C. and Karlin, S. (1997) Prediction of complete gene structures in human genomic DNA.
GENSCAN was developed by Chris Burge in the research group of Samuel Karlin, Department of Mathematics, Stanford University. The program and the model that underlies it are described in: Burge, C. and Karlin, S. (1997) Prediction of complete gene structures in human genomic DNA.
In bioinformatics, GENSCAN is a program to identify complete gene structures in genomic DNA. It is a G HMM -based program that can be used to predict the location of genes and their exon - intron boundaries in genomic sequences from a variety of organisms.
This server provides access to the program GenomeScan for predicting the locations and exon-intron structures of genes in genomic sequences from a variety of organisms. GenomeScan incorporates protein homology information when predicting genes.
Aug 12, 2007 · GENSCAN was easy to use, very fast, and predicted genes in the long sequences of genomic DNA that would characterize the human genome project. Although subsequently shown to predict only 10-15% of genes correctly on realistic genome-wide datasets [4,5], GENSCAN remains a popular bioinformatics tool.
GENSCAN correctly predicts an ORF at ∼ 10% of human gene loci that contain a known ORF (gene sensitivity).
Apr 25, 1997 · GENSCAN is shown to have substantially higher accuracy than existing methods when tested on standardized sets of human and vertebrate genes, with 75 to 80% of exons identified exactly. The program is also capable of indicating fairly accurately the reliability of each predicted exon.
Mar 17, 2000 · The GENSCAN program is designed to predict complete gene structures, including exons, introns, promoter and polyadenylation signals, in genomic sequences.
ORF finder searches for open reading frames (ORFs) in the DNA sequence, returns the range and protein translation of each ORF. Search newly sequenced DNA for potential protein encoding segments, verify predicted proteins with SMARTBLAST or BLASTP.
Sep 1, 2002 · In tests of this program, GRPL matches the performance of Genscan at the nucleotide level (with respect to the correct prediction of exons and introns), but does slightly worse than Genscan at...
