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Jun 17, 2024 · The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.
This makes communication and sharing of data more difficult. The Gene Ontology project provides an ontology of defined terms representing gene product properties. The ontology covers three domains: cellular component, the parts of a cell or its extracellular environment;
An ontology is a formal representation of a body of knowledge within a given domain. Ontologies usually consist of a set of classes (or terms or concepts) with relations that operate between them. The Gene Ontology (GO) describes our knowledge of the biological domain with respect to three aspects: Molecular Function.
The Gene Ontology (GO) project is a major bioinformatics initiative to develop a computational representation of our evolving knowledge of how genes encode biological functions at the molecular, cellular and tissue system levels.
Nov 5, 2018 · The Gene Ontology resource (GO; http://geneontology.org) is the most comprehensive and widely used knowledgebase concerning the functions of genes. In GO, all functional knowledge is structured and represented in a form amenable to computational analysis, which is essential to support modern biological research.
The Gene Ontology is a controlled vocabulary of terms to represent biology in a structured way. The terms are subdivided in three distinct ontologies that represent different
Feb 17, 2011 · The Gene Ontology (GO) project is the largest resource for cataloguing gene function. Nonetheless, its use is not yet ubiquitous and is still fraught with pitfalls. In this review, we provide a short primer to the GO for bioinformaticians.
The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is...
The Gene Ontology (GO) describes knowledge of the biological domain with respect to three aspects: Molecular function; Biological process; Cellular component; A variety of groups, including UniProtKB curators, use GO terms to annotate gene products in a computationally tractable manner. UniProt lists the annotated GO terms in the 'Function ...
Nov 14, 2013 · The Gene Ontology is a dynamic ontology-based resource that provides computationally tractable and human-digestible information about molecular systems. As one of the first and primary biomedical ontologies, the development of the GO pioneered the use of ontologies in computational biology.
