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1,2-di- [ (9Z)-octadecenoyl]-sn-glycero-3-phosphoethanolamine is a 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl substituent both at positions 1 and 2 is specified as (9Z)-octadecenoyl respectively. It has a role as a mouse metabolite. It is functionally related to an oleic acid.
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references. 1,2-Dioleoyl-sn-glycerophosphoethanolamine is a non-bilayer lipid of the phosphatidylethanolamine class, it adopts non-lamellar reverse hexagonal structures. [1] It forms part of Lipofectamine, a common ...
This paper reports results concerning the transfection of gliosarcoma cells 9L using an original cholesterol-based cationic liposome as carrier. This cationic liposome was prepared from triethyl aminopropane carbamoyl cholesterol (TEAPC-Chol) and a helper lipid, dioleoyl phosphatidyl ethanolamine (DOPE). The used
Nov 19, 2014 · The neutral lipid DOPE in cationic lipoplex formulations enables higher transfection efficiencies as the conical structure of this lipid promotes the formation of inverted hexagonal structures ...
Apr 1, 2016 · 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) (Fig. 3), a fusogenic lipid. Early designs of cationic LNPs, alternatively named cationic liposomes, were designed for plasmid DNA delivery for gene therapy [21] and have frequently incorporated DOPE as a helper lipid. In gene delivery, getting the DNA molecule across a membrane, typically ...
Mar 13, 2018 · Structural comparison of DOPC, DOPE and DOPG unsaturated lipids. DOPC (A) contains two fatty-acid chains of 18 carbons each (R) and its headgroup, which is composed of a positively-charged choline ...
DOPE. DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase ...
