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  2. FIRES stands for febrile infection-related epilepsy syndrome, a condition that affects school-aged children after a brief, nonspecific febrile illness. It causes continuous or nearly continuous seizures that are resistant to most medications and can lead to death, chronic epilepsy, or cognitive impairment.

  3. Jul 9, 2019 · Febrile infection-related epilepsy syndrome (FIRES) is a rare catastrophic epileptic encephalopathy with a yet undefined etiology, affecting healthy children. It is characterized by acute manifestation of recurrent seizures or refractory status epilepticus preceded by febrile illness, but without evidence of infectious encephalitis.

    • Domenico Serino, Marta Elena Santarone, Davide Caputo, Lucia Fusco
    • 10.2147/NDT.S177803
    • 2019
    • 2019
  4. Febrile infection-related epilepsy syndrome (FIRES) is a catastrophic epileptic syndrome that strikes previously healthy children aged 3-15 years and has an unknown pathogenesis and few treatments. These children experience a nonspecific febrile illness that is followed by prolonged refractory statu ….

    • Kristy Fox, Mary Ellen Wells, Michael B Tennison, Bradley V Vaughn
    • 2017
  5. Febrile infection-related epilepsy syndrome (FIRES), is onset of severe seizures (status epilepticus) following a febrile illness in someone who was previously healthy. The seizures may initially be focal; however, often become tonic-clonic. Complications often include intellectual disability, behavioral problems, and ongoing seizures.

  6. Nov 17, 2022 · The acronym FIRES stands for febrile infection-related epileptic syndrome, which is a rare epileptic syndrome in the pediatric population. The initial presentation of FIRES is similar to febrile seizures (FS).

  7. FIRES (Febrile infection-related epilepsy syndrome) is a sub-type of cryptogenic new-onset refractory status epilepticus (NORSE). NORSE describes a condition in which a healthy person who has not had seizures before, begins having seizures.

  8. Febrile infection-related epilepsy syndrome (FIRES) is currently classified by the International League Against Epilepsy (ILAE) as an epilepsy syndrome with progressive neurological deterioration beginning in childhood [1]. FIRES has a highly characteristic multiphasic course (Fig. 1).