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Jun 13, 2024 · PLOS Genetics is a peer-reviewed, open access journal that publishes original research articles on all aspects of genetics and evolution. Browse the current issue and discover the latest findings on spindle checkpoint, symbiont ecology, paramutation, giant viruses, and more.
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PLOS Genetics is an Open Access journal that publishes original research in all areas of genetics and genomics. Learn about the journal's criteria for publication, editorial oversight, publication fees, article metrics, and indexing and archiving services.
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Genomic and/or epigenomic analyses in humans or model organisms that provide insight into cancer pathogenesis and/or approaches to therapyIdentification of heritable cancer-susceptibility genes and variantsGenome stability/DNA damage analyses relevant to understanding mechanisms of tumorigenesisCellular/molecular studies that expand understanding of cancer-related signaling pathwaysRegulatory mechanisms controlling genome functions in normal development and in diseaseThe interaction of DNA sequence variability with genome regulationThe molecular and cellular mechanisms mediating the memory of past eventsStudies of molecular or experimental evolution in any organism or systemTheoretical and/or computational approaches that represent a broad advance in understanding evolutionary dynamics and/or mechanismsGenetic and/or genomic whole organism studies that provide insight into adaptation or speciationComputational (“dry bench”) methods and/or molecular genetics (“wet bench”)The methodological advance should be substantial and the new method should be important and likely to be adopted by many researchersDescription of the method must be accompanied by its validation in controlled settings (e.g. simulations) and performance comparisons with existing relevant methodsApplication to an important genetics question and related biological discovery to prove the usefulness of the method is encouraged but not requiredGenome-wide and Phenome-wide association studies (GWAS and PheWAS) that provide new insights on the genetic architecture of human complex traits and diseasesStudies of humans, model organisms, or pathogenic organisms that provide insight into genotype-phenotype relationships at a molecular, organismal, and/or population levelFunctional characterization that elucidates novel mechanisms underlying genotype-phenotype association; experimental studies of genetic pathophysiology for human phenotypesCharacterization of genetic variation in natural populations of humans and human pathogens, which shed light on the history or phenotypic variation of the populationGenetic approaches that provide insights of broad signifcance into the biology of plantsStudies of plant evolution and natural variation and the genetics of agricultural traitsGenomic and epigenomic analyses that provide mechanistic insight into the molecular processes that mediate plant reproduction, development and responses to environmentGenetic approaches that provide insights of broad significance into the biology of bacteria, archaea, or phagesPhenotypic and molecular variation including gene expression, motility, cell cycle regulation, chromosome structure and function, metabolism, biofilm formationMicrobial interactions and microbiomesAuthors may choose the General section if the other sections do not apply. The Editors-in-Chief act as Senior Editors for this section.
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May 7, 2024 · A comprehensive genome-wide cross-trait analysis of sexual factors and uterine leiomyoma. Xueyao Wu, Changfeng Xiao, Danielle Rasooly, Xunying Zhao, Cynthia Casson Morton, Xia Jiang, C. Scott Gallagher. PLOS Genetics: published May 3, 2024 | https://doi.org/10.1371/journal.pgen.1011268.
Learn how to submit your manuscript to PLOS Genetics, a peer-reviewed journal of genetics research. Follow the step-by-step guide to complete the submission form, upload files, and check the requirements and policies.
PLOS Genetics is a peer-reviewed open access scientific journal established in 2005 and published by the Public Library of Science. The founding editor-in-chief was Wayne N. Frankel (Columbia University Medical Center).
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