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Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system.
Jan 18, 2022 · Alpha-blockers can also treat certain conditions even when not specifically approved by the FDA for those conditions. This is known as “off-label” prescribing. It’s often done when there's evidence a medication can treat a condition, and the benefits outweigh the potential risks. Off-label prescribing is legal, medically acceptable and ethical when done safely and responsibly.
Aug 22, 2023 · Alpha blockers are a type of blood pressure medicine. Alpha blockers lower blood pressure by keeping a hormone called norepinephrine from tightening the muscles in the walls of smaller arteries and veins. As a result, the blood vessels remain open and relaxed. This improves blood flow and lowers blood pressure.
Jun 13, 2023 · Alpha-blocker side-effects. Although side-effects are uncommon, they occur in some people. Side-effects are more likely to occur in the first two weeks of treatment and usually go away on their own. The most common side-effects are slight drowsiness, headaches and dizziness. More rarely they can cause sexual problems.
Alpha-1 blockers (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors. They are mainly used to treat benign prostatic hyperplasia (BPH), hypertension and post-traumatic stress disorder. Alpha-1 adrenergic receptors are present in vascular smooth muscle, the central nervous system, and other tissues.
May 6, 2024 · Alpha blockers bind to and block alpha-1 receptors. They are mostly used to treat high blood pressure or symptomatic benign prostatic hypertrophy (BPH) because alpha-1 receptors are located in the smooth muscle lining blood vessels, in the prostate, and in the neck of the bladder.. These conditions are characterized by a tightening (contraction) of smooth muscle because the alpha-1 receptors are stimulated.
Jul 3, 2023 · Alpha-blockers are medications used in the management and treatment of essential hypertension, benign prostatic hyperplasia (BPH), and pheochromocytoma. This activity reviews the indications, contraindications, activity, adverse events, and other key elements of alpha-blocker therapy in the clinical setting as relates to the essential points needed by members of an interprofessional team managing the care of patients with conditions as mentioned above.
Jun 11, 2024 · What are alpha blockers? Alpha blockers are a class of adrenergic blockers that work by antagonizing alpha adrenoceptors in the body. Examples include Cardura, Cardura XL (doxazosin), Minipress (prazosin), terazosin, Flomax (tamsulosin), Uroxatral (alfuzosin ER) , Rapaflo (silodosin), and Dibenzyline (phenoxybenzamine).
May 3, 2024 · Alpha blockers, also called alpha-adrenergic blocking agents, work by interfering with the transfer of messages to specific parts of the body. Like other "blocker" medications, alpha blockers attach themselves to molecules in the body that serve as receptors for certain chemical messages. Because the chemical message is then prevented from reaching its target, it is said to be blocked.
Alpha blockers, also known as alpha-adrenergic antagonists, are used to treat conditions such as high blood pressure, benign prostatic hyperplasia (age-associated prostate gland enlargement that can cause urination difficulty), and Raynaud’s disease, which is a rare circulatory disorder affecting hands and feet. Alpha blockers affect the sympathetic nervous system and work by inhibiting alpha receptors. Alpha receptors are of two types: alpha receptor 1 and alpha receptor 2.
