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  1. Nov 28, 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.

    • Nucleotide Blast

      Nucleotide Blast - Basic Local Alignment Search Tool - BLAST

    • Protein Blast

      Protein Blast - Basic Local Alignment Search Tool - BLAST

    • Blast FAQ

      BLAST cannot recognize, gene names or symbols, protein...

    • Blastx

      Blastx - Basic Local Alignment Search Tool - BLAST

    • Blast

      Local alignments algorithms (such as BLAST) are most often...

    • PMC Free Article Pmc441573

      Basic Local Alignment Search Tool (BLAST) is a sequence...

  2. PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query.

  3. Aug 3, 2023 · BLAST stands for Basic Local Alignment Search Tool. It is a widely used bioinformatics program that was first introduced by Stephen Altschul et al. in 1990 and has since become one of the most popular tools for sequence similarity search.

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  5. Local alignments algorithms (such as BLAST) are most often used. A global alignment should only be used on sequences that share significant similarity over most of their extents, and then it will sometimes return a better presentation.

  6. Mar 21, 2024 · The Basic Local Alignment Search Tool (BLAST) finds regions of similarity between sequences. The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

    • Elliott Smith
    • 2015
  7. BLAST is a computer algorithm that can rapidly align and compare a query DNA sequence with a database of sequences. Learn how BLAST works, its applications in genomic research, and its history and development.

  8. Jul 1, 2004 · Basic Local Alignment Search Tool (BLAST) is a sequence similarity search program that can be used via a web interface or as a stand-alone tool ( 1, 2 ). There are several types of BLAST to compare all combinations of nucleotide or protein queries with nucleotide or protein databases.

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