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  1. Nov 28, 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.

    • Nucleotide Blast

      Nucleotide Blast - Basic Local Alignment Search Tool - BLAST

    • Protein Blast

      Protein Blast - Basic Local Alignment Search Tool - BLAST

    • Blast FAQ

      BLAST cannot recognize, gene names or symbols, protein...

    • Blastx

      Blastx - Basic Local Alignment Search Tool - BLAST

    • BLAST

      Enter one or more queries in the top text box and one or...

  2. PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query.

  3. BLAST is one of the most widely used bioinformatics programs for sequence searching. [4] It addresses a fundamental problem in bioinformatics research. The heuristic algorithm it uses is much faster than other approaches, such as calculating an optimal alignment.

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  5. ElasticBLAST is a suite of command line applications that distributes your BLAST searches across multiple instances in the cloud. It can run large numbers of queries faster than BLAST+ on a single machine and manage cloud resources for you.

  6. Mar 21, 2024 · The Basic Local Alignment Search Tool (BLAST) finds regions of similarity between sequences. The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

    • Elliott Smith
    • 2015
  7. Awash in a sea of data, how do scientists identify the function of a newly cloned gene? Online resources like the Basic Local Alignment Search Tool (BLAST) provide a helping hand.

  8. The program compares nucleotide or protein sequences to sequence in a database and calculates the statistical significance of the matches. This chapter first provides an introduction to BLAST and then describes the practical application of different BLAST programs based on the BLAST Quick Start mini-course (www.ncbi.nlm.nih.gov/Class/minicourses).

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