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Apr 23, 2024 · Ebola disease is caused by an infection with an orthoebolavirus. Orthoebolaviruses are found primarily in sub-Saharan Africa. Orthoebolaviruses can cause serious and often deadly disease, with a mortality rate as high as 80 to 90 percent.
1 day ago · Ebola, infectious disease caused by a virus of the family Filoviridae that is responsible for a severe and often fatal viral hemorrhagic fever. In humans, ebolaviruses cause fatality in 25 to 90 percent of cases. Learn more about the cause, symptoms, treatment, and transmission of Ebola virus disease.
Apr 25, 2024 · Abstract. Ebola virus disease (Ebola) is a rare but severe illness in humans, with an average case fatality rate of approximately 50%. Two licensed vaccines are currently available against Orthoebolavirus zairense, the virus that causes Ebola: the 1-dose rVSVΔG-ZEBOV-GP (ERVEBO [Merck]) and the 2-dose regimen of Ad26.ZEBOV and MVA-BN-Filo (Zabdeno/Mvabea [Johnson & Johnson]).
May 1, 2024 · Efficacy. Clinical efficacy of the vaccine was supported by a randomized cluster vaccination study during the 2014–2016 outbreak in Guinea. In this study, 3,775 people in close contact with someone diagnosed with Ebola disease and their close contacts received immediate vaccination with ERVEBO®.
Ebola virus infection is a notifiable disease. If infection is suspected, the patient should be put in isolation and all healthcare workers in contact with the patient should wear personal protective equipment.
Sep 12, 2015 · Review Methods. For this review, we considered published and unpublished reports related to EBOV and EVD. We reviewed reports from peer-reviewed literature published from 1993 through 2015 and cited in several electronic databases including Medline, PubMed and CINAHL Complete on “Ebola,” “Ebola virus disease,” “Ebola hemorrhagic fever,” “West Africa outbreak,” “Ebola transmission,” “Ebola symptoms and signs,” “Ebola diagnosis,” “Ebola treatment,” “vaccines ...
Apr 25, 2024 · People and animals, including primates, can become infected with a virus that causes Ebola disease from an animal that carries it. People can also get Ebola disease through contact with the body fluids of an infected person or contaminated objects.