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  1. 23 hours ago · An anti-vaccination activist holds a sign at a Tea Party Express rally inside of Minnesota in 2010. Rally of the Anti-Vaccination League of Canada in 1919. Anti-vaccine activism, which collectively constitutes the "anti-vax" movement, is a set of organized activities proclaiming opposition to vaccination, and these collaborating networks have often fought to increase vaccine hesitancy by disseminating vaccine-based misinformation and/or forms of active disinformation.