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  1. Top highlights include the Sistine Chapel, Niccoline Chapel, the Borgia Apartment, and the Gallery of Maps displaying maps created by Roman topographers in the 16th century. You can expect long queues no matter when you visit, so book skip-the-line tickets online to ensure a much shorter wait. Read more.

  2. Catacombe San Sebastiano. 753. Take the 118 city bus from the Colosseum to these catacombs (a route formerly known as the Appian Way and the origin of the saying “all roads lead to Rome”) to see the ancient underground grave where Saint Sebastian was buried in 350 A.D., along with many of Rome’s wealthy Christian families.

  3. Catacombe San Sebastiano. 753. Take the 118 city bus from the Colosseum to these catacombs (a route formerly known as the Appian Way and the origin of the saying “all roads lead to Rome”) to see the ancient underground grave where Saint Sebastian was buried in 350 A.D., along with many of Rome’s wealthy Christian families.

  4. Apr 4, 2024 · San Zeno Chapel at Santa Prassede. The San Zeno Chapel is a small chapel and a major pilgrimage destination inside the church of Santa Prassede (aka Saint Praxedes). The church, chapel, and mosaics all backdate to the 9th century when Pope Paschal I built the chapel and its Byzantine mosaics for his mother.

  5. Sep 1, 2023 · Leonardo Express is the direct train to Termini, it doesn’t stop anywhere else, it reaches in half an hour and costs 14€. The regional train stops at every station, including Trastevere, Ostiense and Tiburtina, it takes 27 minutes to reach Trastevere, 31 to Ostiense, 47 to reach Tiburtina, and it costs 8€.

  6. Catacombe San Sebastiano. 753. Take the 118 city bus from the Colosseum to these catacombs (a route formerly known as the Appian Way and the origin of the saying “all roads lead to Rome”) to see the ancient underground grave where Saint Sebastian was buried in 350 A.D., along with many of Rome’s wealthy Christian families.

  7. CHECK-OUT 12:00 pm. Immerse yourself in the splendour of ancient Rome in a crescent-shaped palazzo fronting the Piazza della Repubblica. Anantara Palazzo Naiadi, one of the best luxury hotels in Rome and the biggest, showcases a uniquely storied history, with 19th-century marble architecture and meeting rooms suspended over the ruins of the ...

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