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MIR122 is a liver-specific microRNA that plays a role in various biological processes, including liver metabolism, viral replication, and hepatocellular carcinoma (HCC) development [].
The mature sequences miR-30 [1] and miR-97 [2] appear to originate from the same precursor. Subsequent data confirm that both arms of the precursor appear to give rise to mature miRNA sequences (Pfeffer S, pers. comm.).
Mmu-mir-21 is a microRNA that participates in cell differentiation by inhibiting genes related to pluripotency, such as Nanog, Sox2, and Pou5f1 [].It is known as a differentiation-state-related miRNA and its highest expression is observed at E11.5 [].
Sep 3, 2018 · The miRBase:Targets database predict targets in the UTRs of 37 different animal genomes from Ensembl [5,7]. miRBase provides a list of mRNAs overlapping each miRNA defining its type (intron, UTR or exon) and the sense (forward or reverse) [7]. miRNAs are often clustered within a genome, therefore, miRBase provides a list of such miRNAs which can be retrieved for any organism. miRBase also displays the distribution of genomic features of miRNAs, showing CpG islands, poly-A site, EST, cDNA ...
Dec 31, 2018 · The latest miRBase version 22 was released in March 2018. In each new released miRBase version, the newly found miRNAs introduced in published literature were added in and the misannotated miRNAs in previous version were corrected or removed. To date, the miRNA numbers and the released time of the 22 primary miRBase versions are shown in Fig. 1.
Examples mentioned by miRBase are the pre-miRNAs hsa-mir-194-1 and hsa-mir-194-2. Release 20 (June 2013) of miRBase contains 24,521 entries representing hairpin precursor miRNAs, expressing 30,424 mature miRNA products, in 206 species. The number reported for H. sapiens includes 1872 precursors and 2578 mature miRNAs.
miRBase: the microRNA database the archive for microRNA sequences and annotations More about miRBase → ...
