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  1. Here we discuss the developmental and homeostatic conditions necessary for Hydra regeneration. Hydra is characterized by populations of adult stem cells paused in the G2 phase of the cell cycle, ready to respond to injury signals. The body column can be compared to a blastema-like structure, populated with multifunctional epithelial stem cells ...

  2. Aug 3, 2023 · Hydra has great power of regeneration as discovered long ago by Abraham Trembley in 1745. Since, then, Hydra has been a favorite material for experimentations on regeneration. If a living Hydra animal is cut into 2 or 3 or more pieces, each missing part grows and becomes a complete animal.

  3. Dec 20, 2022 · Hydra vulgaris is a small and simple aquatic animal capable of whole-body regeneration and has negligible senescence. The entire animal, including the nervous system, is composed of about 25 cell types, and can regenerate from a fragment of tissue as small as ~300 cells. In addition, all cell types are continually renewed in the uninjured adult ...

  4. Nov 1, 2022 · Hydra vulgaris is a small and simple aquatic animal capable of whole-body regeneration and has negligible senescence. The entire animal, including the nervous system, is composed of about 25 cell types, and can regenerate from a fragment of tissue as small as ~300 cells. In addition, all cell types are continually renewed in the uninjured adult ...

  5. Jan 22, 2002 · Hydra is a cnidarian with a simple body plan having a remarkable capacity of regeneration after bisection, trisection, and even after cell dissociation. [6] Hydra regeneration is a dynamic process ...

  6. Fig. 12.2 Regeneration capacities of Hydra vulgaris. The ability of Hydra to regenerate when dissected in various manners and the morphological changes observed are shown. (a) Hydra can regenerate missing parts upon both transverse and longitudinal dissection. (b) Regeneration from dissociated and reaggregated cells.

  7. Aug 23, 2022 · To test whether the regeneration deficiency upon MAPK inhibition, as shown in Fig. 1F, is a direct consequence of aberrant Wnt signaling, we repeated the regeneration assay in the presence of MAPK inhibitors and examined whether recombinant Hydra Wnt3 or Wnt9/10c protein is able to restore the regeneration capacity (Fig. 5C and SI Appendix, Fig. S7).

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